{"id":90,"date":"2025-12-12T21:48:02","date_gmt":"2025-12-12T21:48:02","guid":{"rendered":"https:\/\/cota.org\/cotaforrae\/?p=90"},"modified":"2025-12-16T14:48:13","modified_gmt":"2025-12-16T14:48:13","slug":"more-about-araeya-and-how-ctla4-affects-araeyas-body","status":"publish","type":"post","link":"https:\/\/cota.org\/cotaforrae\/2025\/12\/12\/more-about-araeya-and-how-ctla4-affects-araeyas-body\/","title":{"rendered":"More About Araeya and how CTLA4 Affects Araeya&#8217;s Body"},"content":{"rendered":"\n<p>A quick but very descriptive video about CTLA4 (Araeya&#8217;s genetic disorder):<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"What is CTLA-4 haploinsufficiency? #medical #rare #mentalhealth #hope #survivor #chemotherapy \" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/ekqEBy38rSs?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>For Araeya, her overactive immune system caused by CTLA4 has primarily attacked her lungs and digestive system. She now has Interstitial Lung Disease (ILD) and pre-cancerous cellular change in about 85% of her stomach called Metaplasia. For several years, she has been treated with weekly injections and IV treatments to try and keep her immune system regulated, and the inflamation to a minimum. Unfortunately, the treatments are no longer effective. In April, her Metaplasia was at about 5-10%. When they found it went to 85% in September, the doctors were shocked by how quickly it progressed.<\/p>\n\n\n\n<p>They provided two options: 1. Try different medications and hope they were effective, though there was little evidence in other trials they would be. 2. Move forward with the chemotherapy and bone marrow transplant.<\/p>\n\n\n\n<p>As you know, we chose to move forward with option 2. We believe in a mighty God, and strongly feel this is the path that will lead to Araeya being healthy for the rest of her life. We are thankful for His guidance, your prayers\/love, and the donor&#8217;s selfless sacrifice!<\/p>\n\n\n\n<p><strong>As always, we appreciate you following Araeya&#8217;s journey! We also greatly appreciate your prayers for Araeya, our family, the donor, and the donors family!<\/strong><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A quick but very descriptive video about CTLA4 (Araeya&#8217;s genetic disorder): For Araeya, her overactive immune system caused by CTLA4 has primarily attacked her lungs and digestive system. She now has Interstitial Lung Disease (ILD) and pre-cancerous cellular change in about 85% of her stomach called Metaplasia. For several years, she has been treated with [&hellip;]<\/p>\n","protected":false},"author":2399,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-90","post","type-post","status-publish","format-standard","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.6 (Yoast SEO v26.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>More About Araeya and how CTLA4 Affects Araeya&#039;s Body - COTA for Rae<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cota.org\/cotaforrae\/2025\/12\/12\/more-about-araeya-and-how-ctla4-affects-araeyas-body\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"More About Araeya and how CTLA4 Affects Araeya&#039;s Body\" \/>\n<meta property=\"og:description\" content=\"A quick but very descriptive video about CTLA4 (Araeya&#8217;s genetic disorder): For Araeya, her overactive immune system caused by CTLA4 has primarily attacked her lungs and digestive system. She now has Interstitial Lung Disease (ILD) and pre-cancerous cellular change in about 85% of her stomach called Metaplasia. 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